2017年7月14日 · The 5-HT2A receptor, encoded by the HTR2A gene, is responsible for post-synaptic serotonin signaling and is a target for many antidepressants.

Like all 5-HT 2 receptors, the 5-HT 2A receptor is G q /G 11 -protein coupled. This is the main excitatory receptor subtype among the GPCRs for serotonin. This receptor was first noted for …

HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling. Associations and interactions of the serotonin receptor genes 5-HT1A, 5-HT2A, and …

2024年12月25日 · HTR2A (5-Hydroxytryptamine Receptor 2A) is a Protein Coding gene. Diseases associated with HTR2A include Obsessive-Compulsive Disorder and Major …

RNA sequencing redefined the architecture of the serotonin 2A receptor gene (HTR2A), revealing novel mRNA transcript isoforms utilizing unannotated untranslated regions of the gene. …

2025年2月8日 · Gene target information for HTR2A - 5-hydroxytryptamine receptor 2A (human). Find diseases associated with this biological target and compounds tested against it in …

The 5-hydroxytryptamine 2A receptor, encoded by HTR2A, is a major post-synaptic target for serotonin in the human brain and a therapeutic drug target. Despite hundreds of genetic …

Over the last decade the gene encoding 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) has been implicated as a functional candidate in many neuropsychiatric phenotypes including: …

2016年9月14日 · Gene target information for HTR2A - 5-hydroxytryptamine receptor 2A (human). Find diseases associated with this biological target and compounds tested against it in …

Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538, PubMed:35084960). Affects neural activity, …