2024年12月5日 · A HOXB13 mutation increases the risk for prostate cancer in males. While a HOXB13 mutation means you have a somewhat higher risk of developing cancer than the …

2024年12月25日 · HOXB13 (Homeobox B13) is a Protein Coding gene. Diseases associated with HOXB13 include Prostate Cancer, Hereditary, 9 and Prostate Cancer . Among its related …

The HOXB13 gene provides instructions for producing a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. Learn about this gene and related …

2012年1月12日 · Probands from four families were discovered to have a rare but recurrent mutation (G84E) in HOXB13 (rs138213197), a homeobox transcription factor gene that is …

Prostate cancer has a strong familial component but uncovering the molecular basis for inherited susceptibility for this disease has been challenging. Recently, a rare, recurrent mutation …

2025年3月8日 · Title: Immunoreactivity of HOXB13 in Neuroendocrine Neoplasms Is a Sensitive and Specific Marker of Rectal Well-Differentiated Neuroendocrine Tumors. Germline Variants …

The HOXB13 protein in its normal function plays an important role in urogenital development and maintains high expression levels in the normal prostate into adulthood. Interestingly, all men …

Here we describe our current understanding of HOX signaling in genitourinary development and cancer, current clinical data of HOXB13 mutations in multiple cancers including prostate …

2019年7月4日 · HOXB13, a homeodomain transcription factor, is linked to recurrence following radical prostatectomy. While HOXB13 regulates Androgen Receptor (AR) functions in a …

2022年11月14日 · For many years, a mutated HOXB13 gene was thought to be a risk only for men of Nordic European descent, because the G84E mutation is absent in men of African …