2024年12月25日 · GAD1 (Glutamate Decarboxylase 1) is a Protein Coding gene. Diseases associated with GAD1 include Developmental And Epileptic Encephalopathy 89 and Neurodevelopmental Disorder With Progressive Spasticity And Brain White Matter Abnormalities.

GAD1 mutations are most associated with the autoantigen (another name for an autoimmune target) and T-cell target for the pancreas. Mutations of GAD1 are associated with Type 1 diabetes (1). GAD1 is also associated with a seizure disorder called …

Glutamate decarboxylase 1 (GAD1) is an enzyme encoded for by the gene GAD1 which is only expressed in the brain. GAD1 converts glutamtate into γ-aminobutyric acid (GABA). GABA …

GAD1 gene is associated with ADHD susceptibility. GAD1 is reactivated by DNA methylation, which provided a model for DNA methylation and the active orchestration of oncogenic gene expression by CTCF in cancer cells.

2011年2月7日 · GAD1 is a gene that is associated with the upregulation of HIF-1 and is found in various parts of the brain including the prefrontal cortex and cerebellum. AI generated definition based on: Schizophrenia Research, 2006

Here, we report the identification and characterization of novel mouse GAD1 mRNA splicing isoforms (GenBank: KM102984, KM102985) in addition to the previously described and introduce a new numbering system for the mouse GAD1 exons.

The aim of this study is to identify alternative transcripts of GAD1 that and their expression patterns in the developing PFC, and to identify the transcript and DNA methylation site associated with the genetic risk variant located near the GAD1 promoter. Materials and Methods

2025年2月18日 · Glutamic acid decarboxylase 67 (GAD67) is encoded by the GAD1 gene and is one of the two GAD proteins responsible for the synthesis of the neurotransmitter gamma aminobutyric acid (GABA) from glutamate.

2025年2月8日 · Clinical resource with information about GAD1, Developmental and epileptic encephalopathy 89, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

The GAD1 gene encodes glutamate decarboxylase-67 (GAD67) (L-glutamate-1-carboxylyase; EC 4.1.1.15), an enzyme that catalyzes the conversion of glutamic acid to gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebral central nervous system.