F-box/WD repeat-containing protein 7 is a protein that in humans is encoded by the FBXW7 gene. [5][6][7] This gene encodes a member of the F-box protein family which is characterized by an …

2024年12月25日 · FBXW7 (F-Box And WD Repeat Domain Containing 7) is a Protein Coding gene. Diseases associated with FBXW7 include Developmental Delay, Hypotonia, And …

2018年8月7日 · FBXW7 is a critical tumor suppressor and one of the most commonly deregulated ubiquitin-proteasome system proteins in human cancer. FBXW7 controls proteasome …

FBXW7 (F-Box and WD Repeat Domain Containing 7) (also referred to as FBW7 or hCDC4) is a component of the Skp1-Cdc53 / Cullin-F-box-protein complex (SCF/β-TrCP). As a member of …

2022年4月19日 · In this review, we mainly elaborate on seven hallmarks of cancer influenced by FBXW7, including maintaining growth signals, resisting cell death, inducing angiogenesis, …

The FBXW7 (F-box with 7 tandem WD40) protein encoded by the gene FBXW7 is one of the crucial components of ubiquitin ligase called Skp1-Cullin1-F-box (SCF) complex that aids in …

2023年9月2日 · Low levels of FBXW7 cause abnormal stability of pertinent substrates, mutations and/or deletions in the FBXW7 gene have been reported to correlate with breast cancer …

5 天之前 · F-box and WD repeat domain-containing 7 (FBXW7) is a tumor suppressor that targets various oncoproteins for degradation, but its role in modulating cancer-associated fibroblasts …

Recently, F-box and WD Repeat Domain-containing-7 (FBXW7), a recognized tumor suppressor, has been found to be highly associated with tumor therapy resistance. This review provides a …

2025年2月9日 · FBXW7 polymorphism asserts susceptibility to colorectal cancer. Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 …