Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), also known as G9a, is a histone methyltransferase enzyme that in humans is encoded by the EHMT2 gene. [5] [6] [7] G9a …

2024年12月24日 · EHMT2 (Euchromatic Histone Lysine Methyltransferase 2) is a Protein Coding gene. Diseases associated with EHMT2 include Hyperoxaluria, Primary, Type I and Basan …

2025年2月8日 · Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein. Towards the understanding of the activity of G9a …

2019年11月27日 · Conclusions: This study demonstrates that disrupting EHMT1/2 sensitizes HGSOC cells to PARPi, and suggests a potential mechanism through DNA damage and cell …

2025年2月8日 · SET_EHMT2; SET domain (including pre-SET and post-SET domains) found in euchromatic histone-lysine N-methyltransferase 2 (EHMT2) and similar proteins pfam12796 …

2024年11月3日 · Enables several functions, including C2H2 zinc finger domain binding activity; promoter-specific chromatin binding activity; and protein-lysine N-methyltransferase activity. …

2024年8月7日 · New EHMT1/EHMT2 inhibitors with better brain penetration and oral formulation are needed for neurobehavioral diseases like PWS and AD.

Euchromatic histone lysine methyltransferase 2 (EHMT2) is overexpressed in advanced prostate cancer, restraining catastrophic chromosomal instability (CIN) and enhancing cell fitness. …

Euchromatic histone lysine methyltransferase 2 (EHMT2) is overexpressed in advanced prostate cancer, restraining catastrophic chromosomal instability (CIN) and enhancing cell fitness. …

Dimethylation of the histone H3 protein at lysine residue 9 (H3K9) is mediated by euchromatin histone methyltransferase II (EHMT2) and results in transcriptional repression of target genes. …