DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation. The …

2024年12月24日 · DNMT3A (DNA Methyltransferase 3 Alpha) is a Protein Coding gene. Diseases associated with DNMT3A include Tatton-Brown-Rahman Syndrome and Heyn-Sproul-Jackson …

The DNMT3A gene provides instructions for making an enzyme called DNA methyltransferase 3 alpha. This enzyme is involved in DNA methylation, which is the addition of methyl groups, …

DNMT3A is a methyltransferase enzyme that catalyzes the transfer of methyl groups to cytosines in CpG dinucleotides of DNA. Hence, DNMT3A is an important component for efficient …

2025年3月8日 · Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to …

2010年12月16日 · Using massively parallel DNA sequencing, we identified a somatic mutation in DNMT3A, encoding a DNA methyltransferase, in the genome of cells from a patient with AML …

Profiling of DNMT3A variants revealed a large portion with dramatic loss of DNA methyltransferase activity and protein stability, which enabled the risk stratifi cation of …

DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha) gene encodes the DNA (cytosine-5)-methyltransferase 3A protein, which is involved in epigenetic gene regulation (Gene 2013; …

2022年3月4日 · Very recently, novel roles of DNMT3A in mammalian development have been identified. This makes it necessary for us to re-assess each member of the DNMT3 family …

2015年2月19日 · DNA methyltransferase 3A (DNMT3A) belongs to a family of highly conserved DNA methyltransferases that catalyse 5-methylcytosine methylation. Regulatory domains of …