2024年12月24日 · DDIT3 (DNA Damage Inducible Transcript 3) is a Protein Coding gene. Diseases associated with DDIT3 include Myxoid Liposarcoma and Soft Tissue Sarcoma. …

DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3 gene. [5] [6] It is a member of the …

dna 损伤诱导转录物 3： 该基因编码 ccaat/增强子结合蛋白 (c/ebp) 转录因子家族的成员。该蛋白质通过与其他 c/ebp 成员 (如 c/ebp 和 lap (肝激活蛋白) ) 形成异二聚体并阻止其 dna 结合活 …

2024年10月3日 · This study finds a new role of DDIT3 in promoting necroptosis independently of its known function as a transcription factor; DDIT3 directly binds to p38 and MK2 thereby …

ddit3，即dna损伤诱导转录本3，别名chop、gadd153，是一种转录因子，对细胞应激反应尤其是内质网应激具有关键调控作用。 它通过与ATF4相互作用，促进自噬相关基因表达，并通过抑 …

2025年3月8日 · CEBPZ is a widely used alternative name for DNA damage inducible transcript 3 (DDIT3), which can be confused with the official symbol for CEBPZ (CCAAT enhancer binding …

2022年12月9日 · Overexpression of DDIT3 in human healthy HSCs induces an MDS-like transcriptional state, and dyserythropoiesis, an effect associated with a failure in the activation …

DDIT3, also known as GADD153 or CHOP, encodes a basic leucine zipper transcription factor of the dimer forming C/EBP family. DDIT3 is known as a key regulator of cellular stress …

DDIT3 is induced during glutamine deprivation to promote glycolysis and adenosine triphosphate production via suppression of the negative glycolytic regulator TIGAR. In concert, a proportion …

2024年3月20日 · DNA damage-inducible transcript 3 (DDIT3) gene, mapped to the human chromosome 12q13.3, encodes a protein that belongs to the CCAAT/enhancer-binding protein …