CHD1L, a DNA helicase, possesses chromatin remodeling activity and interacts with PARP1 /PARylation in regulating pluripotency during developmental reprogramming. The CHD1L …

2024年12月24日 · CHD1L (Chromodomain Helicase DNA Binding Protein 1 Like) is a Protein Coding gene. Diseases associated with CHD1L include Hemorrhage, Intracerebral and Renal …

CHD1L is a regulator of chromosomal integrity maintenance, DNA repair and transcriptional regulation through its bindings to DNA. By regulating kinds of complex networks, CHD1L has …

CHD1L (chromodomain helicase/ATPase DNA binding protein 1-like gene) or ALC1 (amplified in liver cancer 1) is a newly identified oncogene located at Chr1q21 and it is amplified in many …

2019年2月4日 · Chromodomain helicase/ATPase DNA binding protein 1-like gene (CHD1L) is a recently identified gene associated with malignant tumor progression and patient...

CHD1L is now considered to be a novel independent biomarker for progression, prognosis and survival in several solid tumors. [Review] Data indicate that chromodomain helicase/ATPase …

Chromodomain helicase/ATPase DNA-binding protein 1-like gene (CHD1L) is a new oncogene which has been confirmed to be crucial to the progression of many solid tumors.

2024年11月1日 · Our findings establish the lead compound C071–0684 as a potent anticancer agent with a novel molecular backbone, demonstrating remarkable efficacy against colorectal …

2013年12月21日 · CHD1L (chromodomain helicase/ATPase DNA binding protein 1-like gene) or ALC1 (amplified in liver cancer 1) is a newly identified oncogene located at Chr1q21 and it is …

2024年1月1日 · CHD1L expression is indicative of poor outcomes and low survival in cancer patients with various cancer types. Herein, we report a set of CHD1L inhibitors (CHD1Li) …