2024年12月24日 · CDK10 (Cyclin Dependent Kinase 10) is a Protein Coding gene. Diseases associated with CDK10 include Al Kaissi Syndrome and Toe Syndactyly, Telecanthus, And …

Cell division protein kinase 10 is an enzyme that in humans is encoded by the CDK10 gene. [5][6][7] The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein …

CDK 亚家族成员与 S. cerevisiae cdc28 和 S. pombe cdc2 的基因产物高度相似，并且已知对细胞周期进程至关重要。 该激酶已被证明在细胞增殖中发挥作用，其功能仅限于细胞周期 G2-M …

CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. Data show that peptidyl-prolyl isomerase Pin1 silencing in SKBR-3 and MCF7 cells …

CDK10 was discovered as early as 1994 by sequence homology screening for CDK-related genes [6, 7]. It displays the central hallmarks of CDKs, bearing more than 40% sequence identity with …

细胞周期蛋白依赖性激酶(cyclin- dependent kinases,CDKs)家族是细胞周期的核心成员,通过与细胞周期蛋白( Cyclins)和细胞周期蛋白依赖性激酶抑制剂(cyclin- dependent kinase …

CDK，即周期蛋白依赖性激酶 (cyclin-dependent kinases)是与细胞周期进程相对应的一套Ser/Thr激酶系统。 各种CDK沿细胞周期时相交替活化，磷酸化相应底物，使细胞周期事件有 …

CDK10 small-molecule inhibitors would be useful in exploring the functions of this kinase and gauging its potential as a therapeutic target for some cancers. Here, we report the …

Cyclin-dependent kinase 10 (CDK10) is a member of the Cdc2 family of kinases, and has been demonstrated to be an important determinant of resistance to endocrine therapy for breast …

2017年7月25日 · Although discovered in the pre-genomic era, CDK10 attracted little attention until it was identified as a major determinant of resistance to endocrine therapy for breast cancer. In …