However, the presence of tumor cells was confirmed through immunostaining with a luciferase antibody (Figure S3D). Next, we performed KI67 staining on PTs and 2-week-old IPTOs and GBOs. ... in the TMZ experiment. 37 We identified several signaling pathways that are upregulated in TMZ-treated tumor cells, including SPP1-CD44, PTN-PTPRZ1, and APP ...
了解详细信息：However, the presence of tumor cells was confirmed through immunostaining with a luciferase antibody (Figure S3D). Next, we performed KI67 staining on PTs and 2-week-old IPTOs and GBOs. ... in the TMZ experiment. 37 We identified several signaling pathways that are upregulated in TMZ-treated tumor cells, including SPP1-CD44, PTN-PTPRZ1, and APP ...
www.cell.com/cell-stem-cell/fulltext/S1934-5909(25…Moreover, the anti-TIGIT treatment group exhibited a pronounced enhancement in the proportion of IFN-γ+ and GRZB+ cells within the CD44+CD8+ T cell subset, relative to the control group (Fig. 6E, F).
www.nature.com/articles/s41419-025-07388-4Based upon the elevated expression levels of Chi3l1 and CD44 in inflamed synovial tissues, the Chi3l1 inhibitor K284-6111 (K284) was encapsulated within the cavity of MgNSPH for synergistic anti-inflammation and anti-ROS, while hyaluronic acid (HA) was incorporated as a targeting moiety into the outer layer of K284@MgNSPH, resulting in the ...
www.sciencedirect.com/science/article/pii/S138589…Studies have shown that glycosylation affects the interaction of collagen with integrins α2β1, α3β1 54, as well as CD44 55. ... protecting mesangial cells from high-glucose-induced damage 94. Elevation in the phosphorylation levels of the breakpoint cluster region of discoidin domain receptor 1, activated by collagen, ...
www.sciencedirect.com/science/article/pii/S221138…A biocompatible and readily available wound dressing for emergencies has been shown to be more cost-effective, while also reducing the risk of immune system-mediated reactions. In this project, we investigated the use of a fresh blood-derived matrix as a wound dressing, based on a 3D drug-loaded Plasma-rich Fibrin (PRF) scaffold, to support the transplantation of autologous stem cells for ...
link.springer.com/article/10.1007/s10561-025-1015…Individualized patient tumor organoids faithfully preserve ... - Cell …
4 天之前 · However, the presence of tumor cells was confirmed through immunostaining with a luciferase antibody (Figure S3D). Next, we performed KI67 staining on PTs and 2-week-old …
TIGIT expression in extrahepatic cholangiocarcinoma and its
3 天之前 · Moreover, the anti-TIGIT treatment group exhibited a pronounced enhancement in the proportion of IFN-γ+ and GRZB+ cells within the CD44+CD8+ T cell subset, relative to the …
Innovative supramolecular coordination nanomedicine: Targeting ...
1 天前 · Based upon the elevated expression levels of Chi3l1 and CD44 in inflamed synovial tissues, the Chi3l1 inhibitor K284-6111 (K284) was encapsulated within the cavity of MgNSPH …
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Post-translational modifications of collagen and its related …
4 天之前 · Studies have shown that glycosylation affects the interaction of collagen with integrins α2β1, α3β1 54, as well as CD44 55. ... protecting mesangial cells from high-glucose-induced …
Plasma-rich fibrin gel and adipose-derived allogeneic …
2 天之前 · A biocompatible and readily available wound dressing for emergencies has been shown to be more cost-effective, while also reducing the risk of immune system-mediated …
Injured proximal tubular epithelial cells lose HNF4A expression …
2 天之前 · The transcription factor hepatocyte nuclear factor 4α (HNF4A) is a key regulator of PT development, controlling the expression of genes central for PT function such as transport and …
Hypoxia-Induced Metabolic and Functional Changes in Oral CSCs ...
2 天之前 · The data for cell viability and cytotoxicity are presented as percentages and fold change, respectively, and statistically described as mean ± SD. (D) Representative confocal …
A single cysteine residue in vimentin regulates long non-coding …
4 天之前 · The labelled cells were washed twice in FCSB and centrifuged at 600 x g for 5 min at RT. The cell pellet was resuspended in azide-free and serum/protein-free PBS and 1 μl of …
Research articles | Cell Discovery - Nature
4 天之前 · Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation. Jie Ruan; Xuxia Wei; Anlong Xu
Browse Articles | Nature Cell Biology
4 天之前 · Loss of homologous recombination allows cells to pass through mitosis, but drives interphase death and inflammation. This suggests a dichotomy between immunogenic and …