Cytochrome P450 4F2 is a protein that in humans is encoded by the CYP4F2 gene. This protein is an enzyme, a type of protein that catalyzes (helps speed up) chemical reactions inside cells.

2024年12月24日 · CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) is a Protein Coding gene. Diseases associated with CYP4F2 include Warfarin Sensitivity and Coumarin …

CYP4F2 is a cytochrome P450 isoform that plays a role in the metabolism of fatty acids and vitamin E [58,59].

A DNA variant (rs2108622; V433M) in cytochrome P450 4F2 (CYP4F2) was associated with warfarin dose in 3 independent white cohorts of patients stabilized on warfarin representing …

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels. Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 …

2023年5月1日 · Compound 18 with inhibitory activity against CYP4A11 and CYP4F2 is obtained by changing the benzene ring to a more hydrophilic pyridine, shortening the linkage chain, and …

These data demonstrate that CYP4F2 is a vitamin K 1 oxidase and that carriers of the CYP4F2 V433M allele have a reduced capacity to metabolize VK1, secondary to an rs2108622 …

In the liver and kidneys, CYP4F2 catalyzes the synthesis of 20-hydroxyeicosatetraeonic acid (20-HETE) from AA. Hepatic CYP4F2 also regulates the bioavailability of vitamin K and vitamin E, …

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels. The frequency of cytochrome 4F2 rs2108622 genetic variant and its effects on the lipid profile and complications …

CYP4F2, CYP4F3A, CYP4F3B, CYP4F8, CYP4F11, CYP4F12, and CYP4F22 are the seven members of the human CYP4F subfamily. These enzymes ω-hydroxylate medium-chain (C10 …