CYP2A6 is the primary enzyme responsible for the oxidation of nicotine and cotinine. It is also involved in the metabolism of several pharmaceuticals, carcinogens, and a number of …

2024年12月24日 · CYP2A6 (Cytochrome P450 Family 2 Subfamily A Member 6) is a Protein Coding gene. Diseases associated with CYP2A6 include Tobacco Addiction and Coumarin …

The CYP2A6 genetic variants impact people's smoking habits, making it easier for some to quit smoking. Check your 23andMe or AncestryDNA genetic data.

As variation in CYP2A6 activity is associated with smoking behavior, smoking cessation, tobacco-related lung cancer risk, and with altered metabolism and resulting clinical responses for …

CYP2A6 is an hepatic enzyme predominantly with some expression in specialized extrahepatic cell types. The CYP2A6 enzyme has a somewhat restricted active site, accepting only a few …

Gene ID: 1548, updated on 8-Feb-2025. This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are …

2012年5月5日 · CYP2A6 differs from other human liver CYP forms in that it participates in the metabolism of very few currently used drugs. The two most relevant substrates for CYP2A6 …

2012年6月1日 · CYP2A6 differs from other human liver CYP forms in that it participates in the metabolism of very few currently used drugs. The two most relevant substrates for CYP2A6 …

CYP2A6, a phase I drug metabolizing enzyme (DME) which metabolizes about 3% of pharmaceutical agents including letrozole, tegafur, coumarin, valproic acid, methoxyflurane, …

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in …