2024年1月16日 · Also has diffuse CAIX but is positive for CD10 and negative or focal for CK7; Loss of chromosome 3p commonly seen Papillary renal cell carcinoma: Clear glycogenated cytoplasm is rare Foamy macrophages and psammoma bodies are common Also usually positive for CK7 but negative or only focal CAIX and often has apical CD10 expression

2022年9月20日 · D. INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high. The tumor shown is small cell carcinoma of the lung. Of the choices listed, INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high (answer D) is the most likely immunoprofile. …

2025年1月7日 · C. PRCC is CAIX negative, CD117 negative, AMACR positive, CK7 patchy, FH retained, TFE3 negative. While CK7 is usually positive in PRCC, it may be negative or focal in high grade PRCC. Answer E is incorrect because clear cell RCC is CAIX positive, CD117 negative, AMACR negative, CK7 negative, FH retained, TFE3 negative.

2014年6月1日 · CK7. CK5 / 6. Calretinin. Positive stains. Cytokeratin AE1 / AE3, cytokeratin 7 (CK7) Calretinin (nuclear ...

2021年3月15日 · CK7, CK20 (variable) (Am J Surg Pathol 2004;28:1352) CDX2 in up to 70% of cases (Arch Pathol Lab Med 2017;141:1155) SATB2 in up to 46% of cases, with patchy and weak staining in most cases, strong and diffuse staining in < 10% of cases (Arch Pathol Lab Med 2017;141:1155) MUC1 (EMA): positive in up to 53% of cases (Am J Clin Pathol 2007;128:808)

2023年5月31日 · CK7, high molecular weight keratins, pankeratins and CK5/6 are positive in the majority of cases but will also stain adenocarcinoma (J Pathol 2002;198:100) PDL1 expression is variable and is scored using tumor proportion score (Lung Cancer 2017;104:7)

Basic (type II) cytokeratins of molecular weight 58 kDa (CK5) and 56 kDa (CK6) (Cell 1982;31:11) Common antibodies are directed against both cytokeratin 5 and 6

Often coexpressed with CK7 Present in both simple and complex epithelium Involved in the organization of myofibers; links contractile apparatus to dystrophin at costameres of striated muscle (also CK8, Mol Biol Cell 2005;16:4280) Polymorphisms of CK19 pseudogene are associated with primary biliary cirrhosis (Hepatol Res 2003;25:281)

2024年4月2日 · Answer A is incorrect because primary Paget disease of the vulva would be negative for uroplakin III and CK20. It is, however, positive for CK7. Answer C is incorrect because vulvar Paget disease secondary to anorectal carcinoma is generally negative for CK7 and uroplakin III. It is, however, positive for CK20.

2020年10月7日 · ck7 Molecular / cytogenetics description FOXL2 402C → G (C134W) somatic mutation is highly sensitive and specific for diagnosis of adult GCT ( N Engl J Med 2009;360:2719 , PLoS One 2009;4:e7988 , Am J Surg Pathol 2011;35:484 )