CD49b is expressed on a fraction of effector T cells in the context of arthritis, influenza or LCMV infection, and in tumors, whereas CD49a expression is largely confined to effector cells …

Cell membrane receptors used to differentiate leukocyte subpopulations. Examples: CD49b, CD34, etc. A family of cytokines that work through G protein–coupled receptors to induce …

In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b − HSCs are highly enriched for myeloid-biased and the …

In this report, we sought to characterize Tregs subsets in a murine melanoma model and disrupt the CD49b/CD29 axis by administering an anti-CD29 antibody in tumor-bearing mice. Our data …

CD49b is expressed on NK cells and a small population of T cells (CD4 + CD3 + TCRα/β +). CD49b is less mouse strain–specific than other NK cell markers (e.g. NK1.1) and is expressed …

2022年7月12日 · In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b - HSCs are highly enriched for myeloid …

2013年4月28日 · By gene expression profiling of human Tr1 cell clones, we identified the surface markers CD49b and lymphocyte activation gene 3 (LAG-3) as being stably and selectively …

This data suggests that CD49b may be a marker of the failure of the immune response and antiviral therapy during HCV recurrence. The assessment of CD49b could help to select …

In a previous study, CD69 was used as an activation marker for NK cells, and DX5 (CD49b) was used as a pan-NK cell marker. By using these markers, NK cell subsets were analyzed in a …

2022年7月12日 · Our studies demonstrate that CD49b can distinguish between functionally and epigenetically distinct multipotent HSCs with myeloid and lymphoid bias in the primitive HSC …