CD154, also known as CD40 ligand, is a costimulatory molecule involved in humoral and adaptive immune responses upon pairing with its classical receptor, CD40. The CD154/CD40 dyad is a …

The interaction between CD40 and CD154 (CD40 ligand) is central in immunology, participating in CD4 + T cell priming by dendritic cells (DC), CD4 + T cell help to B cells and classical …

CD154, also known as CD40 ligand, is a type 2 membrane protein expressed mainly by activated CD4+ T cells and to a lesser extent by other immune cells like CD8+ T cells, NK cells, and …

Full activation of T lymphocytes requires signals from both T cell receptors and costimulatory molecules. In addition to CD28, several T cell molecules could deliver costimulatory signals, …

CD154 is a marker of activation expressed on T cells induced through their T-cell receptor. We analysed CD4 T-cell responses in 72 patients with chronic or resolved HCV infection (23 …

CD154, also known as CD40 ligand (CD40L), previously referred to as gp39, TRAP, or TBAM [2–4], is a 39 kDa type II membrane glycoprotein of the TNF family . Located on the long arm …

CD40 ligand, a type II transmembrane protein recently renamed CD154, was originally considered restricted to activated T lymphocytes, functioning as a mediator of T cell-dependent B cell …

CD154 (CD40L) is a homotrimeric transmembrane TNFα-family protein that is expressed on the surface of activated CD4 + T cells and a wide range of other cell types [1–4]. CD154 can be …

2009年3月11日 · CD154, a member of the tumor necrosis factor-α family, has recently been implicated in the pathophysiology of vascular diseases. Indeed, blockade of CD154 by …

In the current article, we present an overview of the role of CD154 as a potential etiological factor in tumors inducing proliferation of malignant cells, their rescue from apoptosis and their …