C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. [5] . Two ligands have been identified for this receptor: the chemokines (C-C motif) ligand 19 …

2024年12月24日 · CCR7 (C-C Motif Chemokine Receptor 7) is a Protein Coding gene. Diseases associated with CCR7 include Chronic Graft Versus Host Disease and Pars Planitis. Among …

2001年1月15日 · We find that CCR7 is expressed on the vast majority of peripheral blood T cells, including most cells that express adhesion molecules (cutaneous lymphocyte Ag α 4 β 7 …

2008年4月1日 · Recent evidence suggests that by guiding cells to and within lymphoid organs, CC‐chemokine receptor 7 (CCR7) essentially contributes to both immunity and tolerance.

2012年4月25日 · In this review, we summarize the current understanding of the effects of soluble versus immobilized ligands and of the downstream signaling pathways of CCR7 that control …

2022年11月15日 · CC-chemokine receptor 7 (CCR7) is expressed in lymphoid malignancies and is therefore an attractive target for antibody-drug conjugates (ADCs). JBH492 is a novel, …

2019年9月30日 · Migration of CC-chemokine receptor 7 (CCR7)-expressing cells to secondary lymphoid organs is a crucial step in the onset of adaptive immunity, which is initiated by a …

2022年2月24日 · CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell …

2020年4月14日 · CCR7 guides the DCs from the peripheral tissues to the lymph nodes, where these cells control T cell activation. CCR7 can regulate DC chemotaxis, survival, migratory …

2024年2月2日 · CCR7 是一种趋化因子受体，属于七次跨膜 G蛋白偶联受体（GPCR） 家族。 CCR7结构示意图. CCR7的激活可以通过 CCL19 和 CCL21 两种趋化因子来调节。 当CCL19 …