2024年12月24日 · CAND1 (Cullin Associated And Neddylation Dissociated 1) is a Protein Coding gene. Diseases associated with CAND1 include Prostate Cancer and Peroxisome Biogenesis …

Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene. [5] [6] [7]

2023年8月1日 · Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder with high morbidity and mortality. The current study aims to explore the role of Cullin-associated and...

2025年2月9日 · Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation. CAND1 …

2013年3月27日 · Our studies of in vivo cullin 1-RING ubiquitin ligase dynamics and in vitro biochemical findings showing that CAND1 can displace F-box containing substrate receptors …

Pathological cardiac hypertrophy is a process characterized by significant disturbance of protein turnover. Cullin-associated and Neddylation-dissociated 1 (CAND1) acts as a coordinator to …

Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a pivotal component of the ubiquitin-proteasome system, which plays a critical role in regulating protein degradation within …

2018年3月1日 · We established a fluorescence resonance energy transfer (FRET) assay to directly measure the kinetic parameters of Cand1•Cul1, which is an essential prerequisite to …

2020年2月12日 · Immunohistochemical analyses of radical prostatectomy specimens of PCa patients showed that Cand1 protein levels are elevated in PCa compared to benign areas. In …

2023年6月19日 · We describe high-resolution structural intermediates, including a ternary CAND1-SCF complex, as well as conformational and compositional intermediates …