BCL11B Gene - GeneCards | BC11B Protein | BC11B Antibody
2024年12月24日 · BCL11B (BCL11 Transcription Factor B) is a Protein Coding gene. Diseases associated with BCL11B include Intellectual Developmental Disorder With Speech Delay, …
Bcl11b—A Critical Neurodevelopmental Transcription …
B cell leukemia 11b (Bcl11b) is a zinc finger protein transcription factor with a multiplicity of functions. It works as both a genetic suppressor and activator, acting directly, attaching to …
Pivotal role of BCL11B in the immune, hematopoietic and ... - Nature
2024年3月12日 · BCL11B exerts a crucial role in the proliferative response of peripheral CD8+ T-cells in response to viruses, intracellular bacteria and tumors.
BCL11B, the Cerberus of human leukemia | Blood | American …
2021年9月2日 · Recent findings on lineage-promiscuous acute leukemia reveal the BCL11B locus as a multiheaded beast that can drive a variety of immature leukemias, including …
The transcription factor Bcl11b promotes both canonical and
2021年3月12日 · The BCL11B gene, encoding a transcription factor (TF) essential for T cell development and function, was the most extensively regulated, with expression increasing …
BCL11B BCL11 transcription factor B [Homo sapiens (human)]
2024年12月10日 · Title: A Bcl11b (N797K) variant isolated from an immunodeficient patient inhibits early thymocyte development in mice. The function of BCL11B in base excision repair …
BCL11B mutations in patients affected by a neurodevelopmental …
2018年8月1日 · The transcription factor BCL11B is essential for development of the nervous and the immune system, and Bcl11b deficiency results in structural brain defects, reduced learning …
BCL11B BCL11 transcription factor B [ (human)]
2025年2月9日 · Gene ID: 64919, updated on 9-Feb-2025. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be …
Epigenetic Dynamics in the Function of T-Lineage Regulatory Factor Bcl11b
The transcription factor Bcl11b is critically required to support the development of diverse cell types, including T lymphocytes, type 2 innate lymphoid cells, neurons, craniofacial …
Role of the transcription factor Bcl11b in development and ...
Bcl11b is a tumor suppressor and loss of a Bcl11b allele contributes to thymic lymphoma development. On the other hand, Bcl11b is a lineage-specific transcription factor probably …
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