(+)-artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum …

Artemisinin is an antimalarial lactone derived from qinghao (青蒿, Artemisia annua or sweet wormwood). In 1596, Li Shizhen recommended tea made from qinghao specifically to treat …

Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …

2012年8月27日 · After screening of over 5000 traditional Chinese medicines, Qinghaosu (QHS), an antimalarial principle, was isolated from Artemisia annua L in 1972 1, 2. At the end of 1975, …

Artemisinin (qinghaosu) has a unique structure bearing a stable endoperoxide lactone (1,2,13-trioxane) totally different from previous antimalarial in its structure and mode of...

2019年2月1日 · Artemisinin (and its various derivatives, which we will refer to collectively as “artemisinin” unless otherwise specified) is a sesquiterpene lactone compound (Fig. 1) with a …

The unusual tetracyclic structure of 1 containing a peroxidic 1,2,4-trioxane moiety is known to play an essential role in the antimalarial mechanism of action of artemisinin . Interaction of the …