Studying the effects of damage to the ACC provides insights into the type of functions it serves in the intact brain. Behavior that is associated with lesions in the ACC includes: inability to detect errors, severe difficulty with resolving stimulus conflict in a Stroop task, emotional instability, inattention, and akinetic mutism.

2011年4月1日 · The anterior cingulate cortex (ACC) lies in a unique position in the brain, with connections to both the “emotional” limbic system and the “cognitive” prefrontal cortex. Thus, the ACC likely has an important role in integration of neuronal circuitry for affect regulation and can be identified as a distinctive region in understanding ...

2022年8月9日 · The anterior cingulate cortex (ACC) is the front portion of the cingulate cortex (or limbic lobe), a horseshoe-shaped structure near the brain center. The location of the ACC is below the frontal and parietal lobes and surrounding the corpus callosum (a dense layer of nerve fibers lying underneath the cerebral cortex).

2021年6月7日 · The anterior cingulate cortex (ACC) is a region of the human brain (Brodmann area 24, 33, and 34) located at the cingulate cortex’s most frontal part. The ACC wraps around the corpus callosum, a bundle of nerve fibers found beneath the cerebral cortex, and is located before the posterior cingulate cortex (PCC), which is adjacent to the ...

Our results provide a whole-brain mapping of efferent projections from the ACC in adult male mice, and these findings are critical for future studies of the molecular and synaptic mechanisms of the ACC and its related network in mouse models of brain diseases.

2018年7月16日 · Here our findings establish that a projection input from the ACC to the BLA is a critical component of the brain circuitry controlling innate fear responses to predator-related olfactory...

2024年7月17日 · Nature Communications - The anterior cingulate cortex (ACC) is involved in decision strategies. Here the authors show that individual ACC neurons can be dynamically recruited to...

The cytoarchitecture and neurocytology of aMCC point to fundamental differences between the aMCC and anterior cingulate cortex (ACC) (see Figures 3, 4 in ). However, many neuroimaging studies often employ other terminologies such as dorsal ACC to refer to aMCC.

As a ubiquitously active brain region , the ACC reflects a multiplicity of functions in both human and animals. Convergent evidence shows the crucial role of the ACC in a functional circuit that mediates pain processing [13, 231]. In humans, pain processing is complicated and in comorbidity with a wide range of complex states.

2017年9月26日 · The research team showed that when an expected outcome was not delivered, a neural signal in the brain’s ACC was detected. This signal offers clues to the cellular origin of feedback negativity, and that the phenomenon may be generated as the neurons in the ACC shift from encoding expected to actual outcomes.