ABCG2 is a translocation protein used to actively pump drugs and other compounds against their concentration gradient using the bonding and hydrolysis of ATP as the energy source. [1] …

2024年12月24日 · ABCG2 (ATP Binding Cassette Subfamily G Member 2 (JR Blood Group)) is a Protein Coding gene. Diseases associated with ABCG2 include Uric Acid Concentration, …

The ABCG2 gene belongs to a group of genes called the ATP-binding cassette family; genes in this family provide instructions for making proteins that transport molecules across cell …

2021年9月29日 · The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was originally discovered in a multidrug-resistant breast cancer cell line. Studies in …

2019年2月27日 · The ABCG2 gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the …

2015年12月30日 · In addition to the well-known effects of ABCG2 on cytotoxics and targeted agents, ABCG2 is also increasingly linked with failure of PDT, while the role of ABCG2 in …

2017年10月26日 · Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. ABCG2 is an ATP-binding cassette (ABC) transporter that protects tissues against …

2024年10月19日 · Blood samples from 50 patients were assessed using the real-time PCR method. Results: The ABCG2 gene was expressed at a low level in NSCLC, and did not …

Expression, localization, substrates, inhibitors, and drug-drug interactions for ABCG2.

2004年9月8日 · Purpose: The ATP-binding cassette transporter ABCG2 (breast cancer resistance protein) is an efflux protein that plays a role in host detoxification of various xenobiotic …