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Understanding the Role of Phosphodiesterase yhjH on Biofilm Formation ...
2021年5月14日 · YhjH is a phosphodiesterase that degrades bis-(3’5’)-cyclic dimeric guanosine monophosphate (c-di-GMP) and has been shown to play a role in bacterial stress response by …
yhjH:Quickview - EcoliWiki
2013年5月27日 · Overexpressed Salmonella typhimurium YhjH (STM3611) enhances motitility, counteracts cellulose biosynthesis and the rdar phenotype, and mediates cyclic-di-GMP …
The c-di-GMP Binding Protein YcgR Controls Flagellar Motor Direction ...
2010年4月9日 · E. coli and Salmonella have multiple c-di-GMP cyclases and phosphodiesterases, yet absence of a specific phosphodiesterase YhjH impairs motility in both bacteria. yhjH …
The Effect of the Second Messenger c-di-GMP on Bacterial …
In E. coli, the protein YhjH is a phosphodiesterase, which was recently renamed as PdeH following a systematic nomenclature . A wild-type E. coli cell with functional YhjH shows a …
BolA promotes the generation of multicellular behavior in
2024年2月2日 · BolA downregulates the c -di-GMP pathway gene yhjH to inhibit motility. The generation of multicellular behavior enhances the stress adaptability, antibiotic resistance, and …
The Second Messenger c-di-GMP Adjusts Motility and Promotes …
2018年12月4日 · A wild-type cell with functional YhjH shows a minimal level of c-di-GMP; in contrast, a ΔyhjH mutant has elevated c-di-GMP levels (12). We used the E. coli K12 strain …
The EAL domain protein YciR acts as a trigger enzyme in a …
2013年5月24日 · Here, we demonstrate that this system operates as a signalling cascade, in which c‐di‐GMP controlled by the DGC/PDE pair YegE/YhjH (module I) regulates the activity …
Clearance of Pseudomonas aeruginosa foreign-body biofilm
We constructed a Pseudomonas aeruginosa strain in which a reduction in the c-di-GMP level can be achieved via induction of the Escherichia coli YhjH c-di-GMP phosphodiesterase. Initial …
The PilZ Domain Is a Receptor for the Second Messenger c-di …
The yhjH mutation is expected to result in elevated c-di-GMP levels because YhjH is a c-di-GMP phosphodiesterase that strongly affects swimming motility in E. coli and Typhimurium (17, 23, …