Wnt-10a is a protein that in humans is encoded by the WNT10A gene. [5][6][7] The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These …

2003年4月28日 · Classic HED can be diagnosed after infancy based on physical features in most affected individuals. Identification of a hemizygous EDA pathogenic variant in an affected male …

WNT10A gene mutations account for about 5 percent of all cases of hypohidrotic ectodermal dysplasia. Most of the WNT10A gene mutations associated with hypohidrotic ectodermal …

2017年6月7日 · Our data identify WNT10A as a critical ligand controlling adult epithelial proliferation and region-specific differentiation, and suggest downstream β-catenin pathway …

2024年12月25日 · WNT10A (Wnt Family Member 10A) is a Protein Coding gene. Diseases associated with WNT10A include Schopf-Schulz-Passarge Syndrome and …

WNT10A is a member of the WNT proteins family that is essential for the formation of tissues that arise from the ectoderm, including skin, hair, nails, teeth, and sweat glands. WNT10A is …

2019年10月1日 · WNT10A is a member of the WNT proteins family that is essential for the formation of tissues that arise from the ectoderm, including skin, hair, nails, teeth, and sweat …

2025年2月8日 · WNT10A acts as an autocrine oncogene both in renal cell carcinoma carcinogenesis and progression by activating WNT/beta-catenin signaling. In a panel of 34 …

2025年3月1日 · Human wingless-type MMTV integration site family member 10A (WNT10A) is a secreted glycoprotein that is involved in signaling pathways essential to ectodermal …

In this review, we detail how WNT10A is implicated as a key physiological and pathological contributor to syndromic and nonsyndromic disorders, as well as population variants, affecting …