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    Phineas Gage - Wikipedia

    Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior … 展开

    Background
    Gage was the first of five children born to Jesse Eaton Gage and Hannah Trussell (Swetland) Gage of Grafton County, New Hampshire. … 展开

    Mental changes and brain damage 图像

    Harlow saw Gage's survival as demonstrating "the wonderful resources of the system in enduring the shock and in overcoming the effects of so frightful a lesion, and as a beautiful display of the recuperative powers of nature", and listed what he saw as the … 展开

    Portraits 图像

    Though Gage is considered the "index case for personality change due to frontal lobe damage", ​ ​ ​ ​ the uncertain extent of his brain damage​ and the … 展开

    Anatoli Bugorski – scientist whose head was struck by a particle-accelerator proton beam
    Eadweard Muybridge – another early case of head injury leading to mental changes
    Alexis St. … 展开

    概览 图像
    Theoretical misuse 图像

    Gage may have been the first case to suggest the brain's role in determining personality and that damage to specific parts of the brain might induce specific personality changes, but … 展开

    Early medical attitudes 图像
    Factors favoring Gage's survival 图像

    Skepticism
    Barker notes that Harlow's orig­i­nal 1848 report of Gage's sur­viv­al and recov­ery "was widely dis­be­lieved, for obvious reasons"  and Harlow, recall­ing this early skep­ti­cism in his 1868 ret­ro­spec­tive, invoked the biblical story of 展开

    Two daguerreotype portraits of Gage, identi­fied in 2009 and 2010, are the only like­nes­ses​ of him known other than a plaster head cast taken for … 展开

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