In tumors and other proliferating or developing cells, the rate of glucose uptake dramatically increases and lactate is produced, even in the presence of oxygen and fully functioning …

In oncology, the Warburg effect (/ ˈ v ɑːr b ʊər ɡ /) is the observation that most cancers use aerobic glycolysis and lactic acid fermentation for energy generation rather than the …

2021年1月13日 · New research is revealing the mechanisms regulating the Warburg effect, the balance between oxidation and glycolysis of glucose in cancer cells.

Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term maintenance. The common feature of this altered metabolism is the increased glucose uptake …

Anticancer strategies based on the Warburg effect have involved the use of drug compounds and dietary changes. We recently reviewed applications of the Warburg effect to understand the …

2021年5月21日 · The Warburg Effect Is a Prominent Feature of Cancer Cell Metabolism In 1927, Warburg studied the processes of respiration and fermentation in tumor cells. According to …

In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes, most cancer cells …

2009年5月22日 · In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes, most cancer …

2011年1月24日 · The best characterized metabolic phenotype observed in tumour cells is the Warburg effect, which is a shift from ATP generation through oxidative phosphorylation to ATP …

2024年3月8日 · The Warburg effect, characterized by the preferential conversion of glucose to lactate even in the presence of oxygen and functional mitochondria, is a prominent metabolic …