2024年12月25日 · Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden …

2025年2月8日 · LUMA (TMEM43) is a highly conserved protein located to inner nuclear membrane (INM) and interacting with A- and B-type lamins. It is particularly important for …

2022年1月1日 · Our study defined the importance of Tmem43 for cardiac- and metabolism-related pathways, suggesting that cardiovascular disease-relevant risk factors may also increase risk …

Several genes have been identified as pathogenic in arrhythmogenic cardiomyopathy, including TMEM43. However, there are limited data on cardiac MRI findings in patients with TMEM43 …

2024年4月1日 · In this review, we provide a summary of the electrophysiological properties of known TMEM proteins that function as ion channels, such as TMEM175 (K EL), TMEM206 …

2016年12月19日 · Our data show that EGFR recruits TMEM43 following EGF stimulation. TMEM43 interacts with the scaffold protein CARMA3 and its associating complex to induce …

2015年11月8日 · Clinical resource with information about TMEM43, Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia 5, Auditory neuropathy, …

2017年5月18日 · Our data show that EGFR recruits TMEM43 following EGF stimulation. TMEM43 interacts with the scaffold protein CARMA3 and its associating complex to induce downstream …

2024年1月25日 · Background: Transmembrane protein 43 (TMEM43), a member of the TMEM subfamily, is encoded by a highly conserved gene and widely expressed in most species from …

2019年9月5日 · Transgenic mice expressing TMEM43 (transmembrane protein 43)–S358L show fibrofatty replacement of the myocardium and die at a young age. This model confirms that …