Q-band examination did not show the presence of a Y chromosome. This differentiated epithelial substrain (T-47D) was found to contain cytoplasmic junctions and receptors to 17 beta estradiol, other steroids and calcitonin. The cells express the WNT7B oncogene.

2017年5月6日 · Overall, the results highlight the importance of selecting appropriate cell lines for breast cancer studies and suggest that T47D cell lines can be an ideal experimental model to elucidate the progesterone-specific effects of a luminal A subtype of breast cancer.

Establishment and characterization of a cell line of human breast carcinoma origin. Mutations in p53 as potential molecular markers for human breast cancer. Cell lines from human breast.

The T47D xenograft model is an estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), HER2-negative breast cancer model. It is hormone-responsive, making it relevant for studying endocrine therapy resistance.

2017年5月6日 · Although T47D and MCF-7 cell lines represent a luminal A subtype of breast cancer, our analysis suggests that the cell lines exhibit distinct molecular characteristics and that the T47D cell line is an ideal in vitro model for a progesterone-responsive luminal A …

T47D-KBluc is an epithelial cell line that was isolated in 2000 from a pleural effusion of a 54-year-old, female patient with ductal carcinoma of the mammary gland. This cell line was deposited …

The SN38-resistant breast cancer cell sublines T47D/SN120 and T47D/SN150 were established by gradually increasing the concentration of SN38 from 15 nM (IC 50 value) to final concentrations of 120 nM (IC 50 × 8) and 150 nM (IC 50 × 10), respectively in the parental T47D cells.

2014年3月1日 · In this study, T47D cell lines resistant to the antiestrogen fulvestrant were established and analyzed to explore, whether a switch to HER signaling, as seen in fulvestrant resistant MCF-7 cell lines, is a general resistance mechanism.

T-47D (人乳腺管癌细胞) (STR鉴定正确) ￥1600. 细胞培养最优解！ T-47细胞分离自一位54岁乳房侵入性导管癌的女性患者胸水；发现分化的上皮亚株 (T-47D)有细胞质连接和17-β-雌二醇及其他类固醇降血钙素的受体，T-47D细胞表达WNT7B癌基因。 Yes, forms colonies in soft agar. Q：T-47D细胞不加胰岛素的话会影响细胞贴壁吗？ A：胰岛素不添加，细胞生长和增殖可能会受到 …

Protocol for the generation of T47D spheroids, including suggested media and supplements, seeding density, and culture timeline.