1998年10月1日 · Spinocerebellar ataxia type 1 (SCA1) is characterized by progressive cerebellar ataxia, dysarthria, and eventual deterioration of bulbar functions. Early in the disease, affected …

Spinocerebellar ataxia type 1 (SCA1) is a condition characterized by progressive problems with movement. Explore symptoms, inheritance, genetics of this condition.

Spinocerebellar ataxia type 1 (SCA1) is a progressive movement disorder that typically begins in early adulthood (but can affect children and older adults as well). Early signs and symptoms …

SCA1 is caused by a genetic mutation that is passed on from parents to their children. In SCA1, the impairment of nerve cells and nerve fibers causes degeneration of the cerebellum (the …

Spinocerebellar Ataxia type 1 (SCA1) is one specific type of Ataxia among a group of inherited diseases of the central nervous system. In SCA1, genetic defects lead to impairment of …

2023年9月15日 · Spinocerebellar ataxia (SCA) is an inherited (autosomal dominant), progressive, neurodegenerative, and heterogeneous disease that mainly affects the cerebellum. SCA is a …

2016年12月2日 · Spinocerebellar ataxia type 1 (SCA1) is characterized by progressive cerebellar ataxia, dysarthria, and eventual deterioration of bulbar functions. Early in the disease, affected …

SCA1 therapeutics can be classified as genetic, pharmacological, and cell replacement therapies. These different therapeutic strategies target either the (mutant) ATXN1 RNA or the ataxin-1 …

Spinocerebellar ataxia type 1 (SCA1) is a subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term) characterized by dysarthria, writing difficulties, limb ataxia, and …

SCA1, SCA2 (183090), and SCA3, or Machado-Joseph disease (109150), are considered to be forms of ADCA I. These 3 disorders are characterized at the molecular level by CAG repeat …