The gene PSMD4 encodes one of the non-ATPase subunits of the 19S regulator base, subunit Rpn10. Pseudogenes have been identified on chromosomes 10 and 21. [6] . The human …

2024年12月25日 · PSMD4 (Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4) is a Protein Coding gene. Diseases associated with PSMD4 include Cholera and Alzheimer's …

Findings indicated PSMD4 as a subunit of 26S proteasome exerts as an oncogene during tumor development of hepatocellular carcinoma. Preterm delivery is associated with low levels of anti …

2023年5月25日 · Proteomic analysis revealed that inhibiting Rpn10 increased autophagy, antigen presentation, and the activation of CD4+ T and natural killer cells. We developed an in vitro …

Gene/transcipt that contains an open reading frame (ORF). Protein coding. A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest …

PSMD4 (Rpn10, 26S proteasome non-ATPase subunit 4), which is a subunit of the regulatory particle, is a major ubiquitin (Ub) receptor of 26S proteasome. PSMD4 overexpression has …

2023年6月19日 · In this study, transcriptome sequencing of HCC tissues and non-tumor hepatic tissues from the public database Cancer Genome Atlas (TGCA) revealed a high expression of …

We provide evidence that PSMD4 is a proteasomal amplification target in breast cancer that PSMD4 amplification confers sensitivity to PARP inhibition, and that PSMD4 amplification is …

2024年7月7日 · PSMD4 regulates the malignancy of esophageal cancer cells by suppressing endoplasmic reticulum stress. Inhibition of PSMD4 blocks the tumorigenesis of hepatocellular …

2024年11月27日 · Title: PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition. Upregulation of Rpn10 promotes tumor progression via activation …