PSMD1 Gene - GeneCards | PSMD1 Protein | PSMD1 Antibody
2024年12月25日 · PSMD1 (Proteasome 26S Subunit, Non-ATPase 1) is a Protein Coding gene. Diseases associated with PSMD1 include Cystic Fibrosis and Alzheimer's Disease. Among its related pathways are Autodegradation of the E3 ubiquitin ligase COP1 and CDK-mediated phosphorylation and removal of Cdc6.
PSMD1 - Wikipedia
The gene PSMD1 encodes the largest non-ATPase subunit of the 19S regulator base, which is responsible for substrate recognition and binding. [6] The human PSMD1 gene has 25 exons and locates at chromosome band 2q37.1.
Depletion of proteasome subunit PSMD1 induces cancer cell …
2024年4月5日 · PSMD1 depletion decreases the clonal survival of cancer cells, irrespective of p53 status. PSMD1 depletion promotes cancer growth by inhibiting p53 degradation 18.
Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3 …
2021年3月12日 · Luciferase reporter assays and immunoblot analyses demonstrated that PSMD1 and PSMD3 promote NF-κB protein expression in CML, and that signal transducer and activator of transcription 3 (STAT3 ...
蛋白酶体 26S 亚基，非 ATPase 1（PSMD1）基因 | MCE
关于 psmd1 Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:231,056,867-231,172,827 (from NCBI) This gene has 37 transcripts (splice variants), 212 orthologues and 1 paralogue.
PSMD1 proteasome 26S subunit, non-ATPase 1 [ (human)]
PSMD1 as a prognostic marker and potential target in oropharyngeal cancer. Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1).
PSMD1 proteasome 26S subunit, non-ATPase 1 [ Homo sapiens …
2024年12月10日 · Title: Depletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status. PSMD1 as a prognostic marker and potential target in oropharyngeal cancer.
蛋白酶体成分 PSMD1 和 PSMD3 的 NF-κB 依赖性激活作为对伊马 …
PSMD1 和 PSMD3 是 26S 蛋白酶体中 19S 调节复合物的非 ATPase 亚基，可能参与蛋白酶体底物识别和结合。在乳腺癌中，PSMD1 被证明通过诱导 p53 降解来调节细胞生长（Okumura 等人，2018 年），而 PSMD3 被证明可以保护 HER2 免受降解（Fararjeh 等人，2019 年）。
PSMD1 depletion induced cell cycle arrest in G2/M phase, DNA damage and apoptosis of cancer cells, irrespective of the p53 status. PSMD1 depletion‑mediated cell death was accompanied by an...
Proteasome 26S subunit PSMD1 regulates breast cancer cell …
2018年1月1日 · Taken together, PSMD1 was identified as a potential gene that plays a role in the development of tamoxifen resistance in breast cancer cells. These findings will provide a new insight for the mechanism underlying endocrine therapy resistance and a prognostic and therapeutic molecular target for advanced breast cancer.