2023年1月5日 · Yale Medicine neurosurgeon trials a novel treatment for a rare, age-related condition. Normal pressure hydrocephalus (NPH) —a rare condition that causes cognitive and physical symptoms—has traditionally been treated with …

2019年1月4日 · Objective: A short-term lumbar drain (LD) trial is commonly used to assess the response of normal pressure hydrocephalus (NPH) patients to CSF diversion. However, it remains unknown whether the predictors of passing an LD trial match the predictors of improvement after ventriculoperitoneal shunting.

The Placebo-Controlled Efficacy in Idiopathic Normal Pressure Hydrocephalus (iNPH) Shunting (PENS) trial is an investigation of cerebrospinal fluid (CSF) shunt surgery to study the shunt effectiveness in iNPH patients.

2025年3月21日 · A lumbar drainage trial is a diagnostic procedure used to help confirm a diagnosis of normal pressure hydrocephalus (NPH) and to predict whether a patient will benefit from a ventriculoperitoneal shunt (VP shunt).

2024年9月9日 · A new, investigational device has been designed to make the procedure for draining the fluid buildup much easier and potentially safer for patients. VCU Health's NPH neurosurgery team is involved in a groundbreaking clinical trial evaluating the safety and efficacy of the CereVasc® eShunt® Implant.

Placebo-Controlled Efficacy in iNPH Shunting (PENS) is a trial interested in assessing the effectiveness of surgical cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus (iNPH) treatment. iNPH was first described in the 1960s as a form of dementia that can be reversed with ventriculoperitoneal shunting (a surgical treatment).

The STRIDE clinical trial is studying the safety and effectiveness of the eShunt System compared to the VP shunt in people with NPH. The goal of this trial is to see if NPH symptoms, such as problems with walking, improve in people treated with the eShunt System.

2022年7月25日 · The Placebo-Controlled Efficacy in Idiopathic Normal Pressure Hydrocephalus (iNPH) Shunting (PENS) trial is a multi-center blinded, randomized, placebo-controlled design investigation of cerebrospinal fluid (CSF) shunt surgery …

5 天之前 · To participate in the trial, patients must meet the following criteria: Aged 60 or older; ... “Normal pressure hydrocephalus is often difficult to diagnose, but having access to timely detection and prompt treatment can significantly enhance a patient’s quality of life. NPH is a reversible cause of dementia, and we are very excited to see ...

In this issue we bring you key points on recognition, diagnosis, work-up and treatment of normal pressure hydrocephalus (NPH). Recognizing the signs and symptoms of NPH is important as it is currently the only dementia that can be treated.