2024年12月25日 · NFE2L2 (NFE2 Like BZIP Transcription Factor 2) is a Protein Coding gene. Diseases associated with NFE2L2 include Immunodeficiency, Developmental Delay, And …

Our findings revealed the possible role of NFE2L2 across cancers, suggesting that NFE2L2 is a potential prognostic biomarker and is correlated with immune infiltration in many cancers, …

Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. [5] .

NFE2-like basic leucine zipper transcription factor 2 (NFE2L2, also known as NRF2), is a key transcription factor in the cellular defense against oxidative stress, playing a crucial role in …

2015年11月24日 · Nuclear factor, erythroid 2-like 2 (NFE2L2), a transcription factor also known as NF-E2-related factor 2 (Nrf2), is a key cytoprotective gene that regulates critical antioxidant …

NFE2L2 modulates autophagy gene expression and suggests a new strategy to combat proteinopathies. Identify an Nrf2-mediated 17-gene signature, which reflects a cluster of gene …

NFE2L2 is an essential key effector in the sensing of endogenous and environmental oxidative and electrophilic stress in the cell. NFE2L2 is a transcription factor which activates signalling …

2017年10月10日 · Somatic mutations of NFE2L2 leading to NRF2 accumulation promote cell survival and drug resistance in cancer cells. Here we show that the same mutations as inborn …

NFE2L2 is a master regulator of antioxidant/detoxifying system. GABPA controls the transcription of many mitochondrial/metabolic genes. NFE2L2, GABPA and PGC-1alpha are implicated in …

2025年2月9日 · Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. Jang J, et al. Stem Cells, 2014 Oct. PMID 24895273, Free PMC …