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Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), is a potent psychedelic drug that intensifies thoughts, emotions, and sensory perception. Often referred to as acid or lucy, LSD can cause mystical, spiritual, or religious experiences. At higher doses, it primarily induces visual … 展开
LSD, a classical psychedelic, is deemed physiologically safe at standard dosages (50–200 μg) and its primary risks lie in psychological effects … 展开
Pharmacodynamics
Most serotonergic psychedelics are not significantly dopaminergic, and LSD is therefore atypical in this … 展开LSD is a chiral compound with two stereocenters at the carbon atoms C-5 and C-8, so that theoretically four different optical isomers of … 展开
LSD is exceptionally potent, with as little as 20 μg capable of producing a noticeable effect.
Physical
LSD can induce physical … 展开There have been no documented fatal human overdoses from LSD, although there has been no "comprehensive review since the 1950s" and "almost no legal clinical research since the 1970s". Eight individuals who had accidentally consumed an … 展开
Swiss chemist Albert Hofmann first synthesized LSD in 1938 from lysergic acid, a chemical derived from the hydrolysis of ergotamine, an alkaloid found in ergot, … 展开
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