Madin-Darby canine kidney (MDCK) cells are a model mammalian cell line used in biomedical research. MDCK cells are used for a wide variety of cell biology studies including cell polarity, cell-cell adhesions (termed adherens junctions), collective cell motility, toxicity studies, [1] as well as responses to growth

MDCK (NBL-2) cells were isolated from normal kidney tissue from a normal, adult, female cocker spaniel. TMDCK (NBL-2) is used in toxicology and industrial biotechnology research.

MDCK II: Isolated from high passage parental cell line (NBL-2). Type II cells display low TER values (~100 Ω•cm 2) and are positive for claudin-2. They are larger and taller than MDCK I cells and lack gap junctions unless modified. MDCK II cells are the most commonly used MDCK strain and we would recommended them for most studies. Not to be ...

Purchase high quality cryopreserved Madin-Darby canine kidney MDCK II (NBL-2) cells from ECACC for virus studies, transfection, cell polarity, migration/invasion.

The Madin-Darby Canine Kidney (MDCK) cell line is widely used as epithelial cell model in studies ranging from viral infection to environmental pollutants, and vaccines production. However, little is known about basal expression of genes involved in ...

MDCK.2 is an epithelial-like cell that was isolated from the distal renal tubule of a dog. This cell line was deposited by Y. Reid, E. Cedrone, E-Eckard-Amar, and can be used in toxicology research.

The goal of this work was to investigate the use of MDCK (Madin-Darby canine kidney) cells as a possible tool for assessing the membrane permeability properties of early drug discovery compounds. Apparent permeability (Papp) values of 55 compounds with known human absorption values were determined u …