2024年11月21日 · Hemolytic disease of the newborn (HDN) refers to an immune hemolytic disease caused by blood group incompatibility between a mother and fetus. It is a common cause of neonatal jaundice and anemia. Thus far, over 40 blood group systems and 350 red blood cell group antigens have been identified, all of which have immunogenic potential [1].

新生兒溶血症（HDN, Hemolytic disease of the fetus and newborn）是一種第二型過敏反應，是由於母親和胎兒的血型不同而引起的疾病。 若母親體內有對抗胎兒血型的 抗體 ，這些抗體便會經過 胎盤 ，進入胎兒體內，攻擊胎兒的 紅血球 ，引起 溶血反應 ，导致婴儿出现 貧 ...

In the space of most paediatricians working lifetime, the spectrum of haemolytic disease of the newborn (HDN) has changed beyond recognition. Thirty years ago, HDN was almost synonymous with Rh D allo‐immunisation and was a common neonatal problem.

Haemolytic disease of the foetus and newborn (HDFN) is most commonly due to red cell alloimmunisation. In HDFN, maternal immunoglobulin antibodies directed against foetal red blood cells pass through the placenta into the foetal circulation and cause the destruction of …

新生儿溶血病（hemolytic disease of newborn，HDN）指母婴血型不合引起的同族免疫性溶血（isoimmune hemolytic disease）。 在已发现的人类26个血型系统，以ABO血型不合最常见，Rh血型不合较少见。

同种免疫性新生儿溶血病 (hemolytic disease of the newborn, HDN)，又称胎儿和新生儿溶血性疾病 (hemolytic disease of the fetus and newborn, HDFN)，是胎儿或新生儿的红细胞被母体IgG抗体破坏所致。 母体内未表达的红细胞抗原通过胎儿或其他外源性来源 (输血)进入母体循环时，就会产生这些抗体，该过程称为敏化。 本专题将总结同种免疫性HDN的产后诊断和治疗。 产前诊断和治疗详见其他专题。 (参见 “妊娠期非RhD红细胞同种抗体的管理” 和 “妊娠期RhD同种异体免疫 …

2020年11月3日 · Hemolytic disease of the newborn (HDN) occurs due to maternal IgG antibodies crossing the placenta, thereby producing hemolysis mainly due to Rh incompatibility and to a lesser extent by ABO and Kell groups. Clinical presentation of HDN depends upon the severity of red cell lysis. It may develop mild jaundice and anemia to hydrops fetalis.

The Kidd blood group is clinically significant since the Jk antibodies can cause acute and delayed transfusion reactions as well as hemolytic disease of newborn (HDN). In general, HDN due to anti-Jk b incompatibility is rare and it usually displays mild

2022年8月1日 · Hemolytic disease of the newborn (HDN), also known as Erythr oblastosis fetalis, is a hemolytic disorder that primarily affects Rhesus positive (Rh+) fetuses and new - borns...

新生儿溶血病（hemolytic disease of newborn，HDN）是指由母体和胎儿的血型不同引起胎儿或新生儿的一种溶血。 人类发现有多种血型系统，其中 ABO 血型不合最常见，其次为 Rh 血型不合，症状较严重。