
Department of Defense Impact Level 4 - Azure Compliance
2023年4月4日 · DoD IL4 overview. The Defense Information Systems Agency (DISA) is an agency of the US Department of Defense (DoD) that is responsible for developing and …
Interleukin 4 - Wikipedia
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …
Recent advances in understanding the role of IL-4 signaling
STAT6 is so vital for the actions of IL-4 that Stat6-deficient mice phenocopy many of the defects observed with Il4- or Il4ra-deficient mice (e.g., related to Th2 differentiation and Ig class switch).
IL4 Gene - GeneCards | IL4 Protein | IL4 Antibody
2024年12月25日 · IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway …
Interleukin-4: A Cytokine to Remember - PMC
IL-4 plays important roles in a myriad of cellular events, making it difficult to study its effects, particularly in vivo, on any one system. Although this review focuses on its neurological …
Recent advances in understanding the role of IL-4 signaling
2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …
IL4 Signaling: Pathways, Receptors, and Immune Functions
2025年3月20日 · Genetic polymorphisms in IL4 and IL4R genes have been linked to allergic disorder susceptibility. Targeting IL-4 signaling has led to therapies like dupilumab, a …
IL4 interleukin 4 [Homo sapiens (human)] - Gene - NCBI
2025年2月8日 · IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway …
Regulation of IL4 gene expression by T cells and therapeutic ...
2003年7月1日 · Acute expression of the IL4 gene by differentiated T H 2 cells is regulated by many positive and negative inducible transcription factors, such as nuclear factor of activated …
Interleukin 4, Serum - Lab Results explained | HealthMatters.io
Interleukin-4 (IL4) is a growth factor for both B and T lymphocytes. - High levels of IL4Rs have been observed on tumors derived from such cells. - IL4Rs are also overexpressed on …