Glutathione peroxidase 4 - Wikipedia
GPX4 is a phospholipid hydroperoxidase that protects cells against membrane lipid peroxidation. GPX4 was first discovered in biochemistry laboratories of the University of Padua, where it …
GPX4 Gene - GeneCards | GPX4 Protein | GPX4 Antibody
2024年12月25日 · GPX4 (Glutathione Peroxidase 4) is a Protein Coding gene. Diseases associated with GPX4 include Spondylometaphyseal Dysplasia, Sedaghatian Type and Bone …
GPX4: The hub of lipid oxidation, ferroptosis, disease and ...
Glutathione peroxidase 4 (GPx4) moonlights as structural protein and antioxidase that powerfully inhibits lipid oxidation. In the past years, it is considered as a key regulator of ferroptosis, …
GPX4-independent ferroptosis—a new strategy in disease’s ...
2022年10月30日 · Glutathione peroxidase 4 (GPX4) acts as a master regulator in the ferroptosis process, and its unique function is to interrupt lipid peroxidation by converting lipid …
GPX4 in cell death, autophagy, and disease - PMC
In this review, we first describe the structure and function of GPX4, then outline the novel roles of GPX4 in cell death and autophagy, and finally discuss the impact of GPX4 on embryonic …
GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis
The lipid hydroperoxidase glutathione peroxidase 4 (GPX4) converts lipid hydroperoxides to lipid alcohols, and this process prevents the iron (Fe 2+ )-dependent formation of toxic lipid reactive …
The Selenoprotein Glutathione Peroxidase 4: From Molecular ...
The selenoprotein glutathione peroxidase 4 (GPX4) is one of the main antioxidant mediators in the human body. Its central function involves the reduction of complex hydroperoxides into …