
Granulocyte-macrophage colony-stimulating factor - Wikipedia
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine.
GM-CSF: A Promising Target in Inflammation and Autoimmunity
The cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), was firstly identified as being able to induce in vitro the proliferation and differentiation of bone marrow progenitors into granulocytes and macrophages. Much preclinical ...
GM-CSF: A Double-Edged Sword in Cancer Immunotherapy
2022年7月5日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and dendritic cells in response to stress, infections, and cancers.
GM-CSF: a role in immune and inflammatory reactions in the …
Granulocyte macrophage colony-stimulating factor (GM-CSF) is a cytokine that promotes myeloid cell development and maturation, and dendritic cell differentiation and survival in vitro. Growing evidence supports the notion that GM-CSF has a major ...
Granulocyte-macrophage colony-stimulating factor (GM-CSF) …
2006年2月13日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic growth factor and immune modulator. GM-CSF also has profound effects on the functional activities...
Clinical uses of GM-CSF, a critical appraisal and update - PMC
The role of granulocyte-macrophage-colony-stimulating factor (GM-CSF) in the supportive care of cancer patients has been evaluated with promising results. More recently, GM-CSF has been added to regimens for the mobilization of hematopoietic ...
Granulocyte-macrophage colony-stimulating factor: an ... - Nature
2021年7月19日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF), which belongs to the colony-stimulating factor (CSF) superfamily and was originally identified as a hemopoietic growth factor,...
GM-CSF in inflammation - PubMed
2020年1月6日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) has many more functions than its original in vitro identification as an inducer of granulocyte and macrophage development from progenitor cells.
GM-CSF: Benefits, Uses, and Side Effects Explained
GM-CSF, or granulocyte-macrophage colony-stimulating factor, is a powerful medication that can help boost your immune system, particularly in cancer treatment or bone marrow recovery. However, like all medications, it comes with potential side effects and risks that should be carefully considered.
GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation
2016年11月15日 · GM-CSF has initially been categorized as a hematopoietic growth factor involved in steady-state myelopoiesis. However, it now emerges as a critical communication conduit between lymphocytes and myeloid cells in inflammation.