Formyl peptide receptor 2 - Wikipedia
FPR2 is also known as the LXA4 or ALX/FPR2 receptor based on studies finding that is a high affinity receptor for the arachidonic acid metabolite, lipoxin A4 (LXA4), and thereafter for a …
FPR2 Gene - GeneCards | FPR2 Protein | FPR2 Antibody
2024年12月25日 · FPR2 (Formyl Peptide Receptor 2) is a Protein Coding gene. Diseases associated with FPR2 include Prion Disease and Diamond-Blackfan Anemia 2. Among its …
Formyl peptide receptor 2 is an emerging modulator of ... - Nature
2023年2月7日 · We shed light on the dual action of FPR2 in the liver and discuss the hepatoprotective roles of FPR2 itself and FPR2 agonists in mediating anti-inflammatory …
Metabolic signaling of ceramides through the FPR2 receptor
2025年3月13日 · Ceramides play a central role in human health and disease, yet their role as systemic signaling molecules remain poorly understood. In this work, we identify FPR2 as a …
Formyl peptide receptor 2, as an important target for ligands ...
Among them, FPR2 is a low affinity receptor for N-formyl peptides and is considered the most promiscuous member of FPRs. FPR2 is able to recognize a broad variety of endogenous or …
FPR2 formyl peptide receptor 2 [ (human)] - National Center for ...
The structure of FPR2 reveals a widely open extracellular region with an amphiphilic environment for ligand binding. Formyl-peptide receptor 2 suppresses proliferation, migration and invasion …
Metabolic signaling of ceramides through the FPR2 receptor …
2025年3月13日 · In brown and beige adipocytes, C16:0 ceramide binding to FPR2 inhibits thermogenesis via G i-cyclic AMP signaling pathways, an effect that is reversed in the …
Formyl peptide receptors in the mucosal immune system
2020年10月20日 · There are three types of human FPRs (FPR1, FPR2, and FPR3) and eight types of murine FPRs (Fpr1, Fpr2, Fpr3 (Fpr-rs1), and Fpr-rs3 to 7). FPR1 was the first …
The formyl peptide receptors FPR1 and FPR2 as targets
2024年2月5日 · Formyl peptide receptors (FPRs) comprise a class of chemoattractant pattern recognition receptors, for which several physiological functions like host…
Formyl peptide receptor 2 is regulated by RNA mimics and ... - PubMed
Formyl peptide receptor 2 (FPR2) recognizes numerous proinflammatory and anti-inflammatory stimuli, and emerging reports indicate elevated levels of FPR2 in several disease conditions.