2018年9月21日 · We show that Connexin 43 (Cx43) controls neural crest cell migration in vivo by directly regulating N-cadherin transcription. This activity requires interaction between Cx43 carboxy tail and...

5 天之前 · Flight status, tracking, and historical data for Cathay Pacific 43 (CX43/CPA43) including scheduled, estimated, and actual departure and arrival times.

2019年7月26日 · Connexin43 (Cx43) is commonly associated with direct cell–cell communication through gap junctions (GJs). However, recent groundbreaking studies have challenged this dogma, implicating Cx43 in other biological processes, such as transcription, metabolism, autophagy, and ion channel trafficking.

2022年2月10日 · Connexin 43 (Cx43) is the most abundant connexin expressed in astrocytes and forms the gap junction channels (GJCs) between astrocytes, the most abundant and functional glial cells in the brain.

Connexin-43 (Cx43) is the main connexin in ventricular cardiomyocytes; it is synthesized in the endoplasmic reticulum, oligomerized in the Golgi apparatus and delivered to the sarcolemma as closed hemichannels.

2024年12月25日 · GJA1 (Gap Junction Protein Alpha 1) is a Protein Coding gene. Diseases associated with GJA1 include Oculodentodigital Dysplasia and Syndactyly, Type Iii. Among its related pathways are Gap junction trafficking and Infectious disease.

Connexin43 (Cx43), the most widely expressed and abundant vertebrate gap junction protein, is phosphorylated at multiple different serine residues during its life cycle. Cx43 is phosphorylated soon after synthesis and phosphorylation changes as it ...

Cx43 phosphorylation can affect changes in Cx43-interacting protein binding, subsequently affecting the underlying signaling pathways of gap junction communication, hemichannel function, kinase activity, and cell biological function.

2019年2月1日 · Over the last few years, aberrant connexin 43 (Cx43) expression has been associated with cancer recurrence, metastatic spread, and poor survival. Here we provide an overview of the general structure and function of gap junctions and review their roles in …

2020年9月29日 · Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are …