Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene. [3] [4] This gene is …

Complement receptors CD21 and CD35, which recognize activated products of C3 and C4, are predominantly expressed on B cells and follicular dendritic cells (FDCs) in the mouse. In this …

CD35, also known as complement receptor 1 (CR1), is a cell surface glycoprotein distributed on the surface of a variety of cells, including red blood cells, granulocytes, monocytes, mast cells, …

First, CD21 and CD35 may enhance and prolong humoral responses by focusing and retaining antigen/antibody/complement complexes (35–38); second, complement-decorated antigens …

1997年9月1日 · Molecular definition of the cellular receptor for the collagen domain of C1q has been elusive. We now report that C1q binds specifically to human CR1 (CD35), the leukocyte …

Our functional studies show that after clustering CR1 both by its natural ligand and To5 mAb, the inhibitory function of CD35 is maintained in RA patients, despite its significantly reduced …

2013年2月21日 · Human CD35 is an independent membrane gp best studied as an immune adherence and phagocyte receptor. A regulator of C′ activity (RCA) gene family member, …

The role of complement in the regulation of T cell immunity has been highlighted recently by several groups. We were prompted to reinvestigate the role of complement receptor type 1 …

Our studies underscore the potential importance of CR1 on an epithelial cell population as both an intrinsic complement regulator and an immune adherence receptor. These results provide a …

CD35, also known as complement receptor 1 (CR1), is a protein found on the surface of various immune cells that plays a vital role in the immune response by facilitating the clearance of …