CD29 is widely expressed in human salivary glands and, it could serve as a potential biomarker for devising novel cellular therapeutic and diagnostic strategies for salivary gland disorders and malignancies. Keywords: Adult, CD29, fetal, progenitor, salivary gland, stem cells. Introduction

CD29 is widely expressed in human salivary glands, and it could serve as a potential biomarker for devising novel cellular therapeutic and diagnostic strategies for salivary gland disorders and malignancies.

2023年11月6日 · In addition, integrin β1, also recognized as CD29, which is one of the most common subunits in the integrin family and is composed of a β1 subunit and different α subunits, plays a non-negligible role in crucial developmental pathways.

2020年3月11日 · CD29 gene signature is associated with better survival, and CD29 + T cells are superior in killing tumor cells. (A and B) Kaplan–Meier plots of overall survival of (A) all patients suffering from SKCM or (B) of patients with high CD8 + T cell infiltrate estimates.

Recent evidence suggests that CD29 is an upstream regulator of Actopaxin, and their expressions in HCC are significantly positively correlated, moreover, there is a close relationship between the expression level of Actopaxin and the activity and phosphorylation of CD29 (Ng et al., 2013). Specifically, HCC cells with higher expression of CD29 ...

CD29 is a marker expressed by CD133+ cells, which are found in adult human renal cortical parenchyma. These cells also co-express other markers of mesenchymal cells like CD73 and CD44. AI generated definition based on: Current Opinion in Pharmacology, 2006

2020年3月24日 · Preselecting CD29-expressing MART1 TCR-engineered T cells potentiated the killing of target cells. We therefore propose that CD29 expression can help evaluate and select for potent therapeutic T cell products.

2021年12月15日 · CD29 expression enriched for CD4 + T cells, which effectively produced the proinflammatory cytokines IFN-γ, IL-2, and TNF-α, and cytotoxic molecules. Lastly, CD29-expressing CD4 + T cells transduced with a MART1-specific TCR showed target cell killing in …

Increased levels of CD25 (the IL-2 receptor) and the activation marker CD69 can be found at the early stages of T cell activation, whereas the marker CD29 appears only very late in activation. Activated, but not resting, T cells also express the intercellular adhesion molecule CD54, the activation regulator CD27, and the costimulatory molecule ...

2021年12月15日 · CD29 expression enriched for CD4 + T cells that produced cytotoxic molecules such as granulysin and granzymes, and the proinflammatory cytokines IFN-γ, IL-2, and TNF-α.