The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha …

CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The …

IL-2 binds to the IL-2 receptor, which has three forms, generated by different combinations of three different proteins, often referred to as "chains": α (alpha) (also called IL-2Rα, CD25, or …

Elevated levels of soluble interleukin-2 receptor α-chain (IL-2Ra/CD25) are detected in the serum of patients with a broad spectrum of conditions associated with T- or B-cell immune activation, …

Immunodeficiency due to CD25 deficiency is a rare, genetic, primary immunodeficiency due to a defect in adaptive immunity disorder characterized by severe immunodeficiency, presenting …

CD25, or Soluble Interleukin 2 Receptor, is an integral part of your immune system, facilitating communication between immune cells and coordinating the body's defense against illness and …

CD25 is a cell-surface marker on activated lymphocytes which is involved in cellular immune responses. CD25 can serve as a biomarker for autoimmune disorders and cancer.

2025年3月20日 · A key feature of Tregs is the expression of CD25, the alpha chain of the interleukin-2 receptor (IL-2R), which is essential for their function and survival. Understanding …

CD25, also known as the interleukin-2 receptor alpha chain (IL-2Rα), is a protein found on the surface of certain immune cells, particularly activated T cells and regulatory T cells (Tregs).

CD25, the alpha chain of the IL-2 receptor, is highly expressed on intratumoral Tregs, making it an attractive target for selective depletion. PF-08046032 is a novel antibody-drug conjugate …