CD15 is present on almost all Reed–Sternberg cells, including their rare mononuclear variants, and, as such, can be used in immunohistochemistry to identify the presence of such cells in biopsies. The presence of these cells is diagnostic of Hodgkin's lymphoma.

2008年10月19日 · The glycan determinant CD15 (also known as Lewis x, or Lex) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells.

CD15, the X hapten or Lewis X antigen, can be identified with the LeuM1 antibody. Originally noted as a monocyte/myeloid cell marker, it was recognized as a marker for the Reed-Sternberg cells of classical Hodgkin lymphoma.

CD15 (3-fucosyl-N-acetyl-lactosamine) is a cluster of differentiation antigen – an immunologically significant molecule. CD15 is a carbohydrate adhesion molecule (1) that can be expressed on glycoproteins, glycolipids and proteoglycans.

The Lewis x (Le x) antigen, or CD15, is a cell surface glycan consisting of a trisaccharide with the structure Galβ1-4 [Fucα1-3]GlcNAc. Initially identified by monoclonal antibodies in the early 1980’s, it was quickly appreciated as a useful marker for human myeloid differentiation 1,2, in particular, in identifying granulocyte-series cells.

The glycan determinant CD15 (also known as Lewis x, or Le (x)) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells.

CD15 This is a retired HUGO symbol for what molecular biologists now term FUT4 (see there). In practice, CD15 is widely used by haematologists, immunologists, laboratorians, pathologists and many others.

2022年4月28日 · CD15 (Lewis X/Lex) is a fucosyl (3-fucosly-N-acetyl-lactosamine) moiety found on membrane proteins of various cancer cells. These cancers include renal cancer, prostate and bladder cancers, acute leukaemias, hepatocellular carcinoma, breast cancer and melanoma.

CD15 is a haemopoietic differentiation antigen expressed on most terminally differentiated myeloid cells including granulocytes, eosinophils, mast cells, monocytes/macrophages, and Langerhans’ cells.

We performed a genome-wide analysis of gene expression in primary human CD15 + myeloid progenitor cells. By using the serial analysis of gene expression (SAGE) technique, we obtained quantitative information for the expression of 37,519 unique SAGE-tag sequences.