Calu-3 is a cell line obtained from a male, lung adenocarcinoma patient that can be used in cancer and toxicology research.

Calu-3 is a human lung cancer cell line commonly used in cancer research and drug development. Calu-3 cells are epithelial and can act as respiratory models in preclinical …

This article reviews the application of the human airway Calu-3 cell line as a respiratory model for studying the effects of gas concentrations, exposure time, biophysical stress, and biological …

2020年10月22日 · Calu-3 cells are a submucosal gland cell line, which was generated from a bronchial adenocarcinoma. Under air–liquid interface conditions Calu-3 cells grow in …

Calu-3 is a non-small-cell lung cancer cell line that grows in adherent culture and displays epithelial morphology. These cells have constitutively active ErbB2/Her2 due to amplification …

Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion. Demonstration of an interferon gamma-dependent tumor surveillance system in …

Calu-3 cells constitute a human-derived airway epithelial cell line representing non-small cell lung carcinoma. They are widely used in biomedical research that includes studying lung cancer …

The Calu-3 tumor model is a well-established xenograft model to study the effects therapeutics, such as erlotinib, trastuzumab and pertuzumab on HER2 and EGFR expressing cells. Calu-3 …

The Calu-3 CDX mouse model enables investigation of human lung cancer cell therapeutics targeting migration, apoptosis, anti-angiogenesis and anti-tumor growth in a human-similar …

Calu-3 cells formed polarized monolayers with tight junctions and Rte of approximately 100 omega.cm2. Baseline Isc was approximately 35 microA/cm2 and was increased by …

The results show that Calu-3 fully polarize when grown on permeable supports as liquid-covered cultures. Polarized Calu-3 are susceptible to RSV infection and release infectious virus …

2021年3月23日 · Here, we developed a 3D model of the human bronchial epithelium using Calu-3 cell line and demonstrated its viability and functionality for 21 days without subculturing.

Calu-3 cells exposed to graded oxygen concentrations demonstrate cell dysfunction and inflammation in a dose-dependent manner. Modeling positive airway pressure reveals that …

In this study, we report differences in response of Calu-3 epithelial cells to exogenous stimuli Staphylococcus aureus enterotoxin B (SEB) and house dust mite (HDM) extract compared to …

The Calu-3 cell line can assist in finding potential drug therapies and has shown to be useful in mimicking in vivo conditions.3 This similarity has allowed for many pharmaceutical applications …

2010年6月27日 · This article reviews the application of the human airway Calu-3 cell line as a respiratory model for studying the effects of gas concentrations, exposure time, biophysical …

Cell culture models such as Calu-3 provide a simple and reproducible system to study the underlying mechanisms by which inhaled therapeutics interact with the lungs.

2015年3月10日 · In this study we have investigated the effects of different cell culture conditions on the Calu-3 epithelial cell model. Calu-3 cells were cultured in media A-MEM at the air–liquid …

CALU-3 cells cultivated onto CellFate® resulted in a pseudostratified organization, a typical morphology of the human respiratory tract epithelium. The current model opens perspectives …