
CD30 - Wikipedia
CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), [5] is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker for anaplastic large cell …
Pathology Outlines - CD30
CD30, also known as BerH2, Ki1 or TNFRSF8, is a transmembrane glycoprotein receptor that belongs to the tumor necrosis factor receptor (TNFR) and was first identified in Hodgkin …
Understanding CD30 biology and therapeutic targeting: a ... - Nature
2017年9月8日 · CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically expressed in certain hematopoietic malignancies, including anaplastic large …
The Polyvalent Role of CD30 for Cancer Diagnosis and Treatment
CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well as a tumor …
CD30 + lymphoproliferative disorders - PubMed Central (PMC)
CD30 antigen, originally identified as a cell surface marker of the malignant Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin’s lymphoma by the use of the Ki-1 monoclonal antibody, is a …
CD30: expression and function in health and disease - PubMed
CD30 was originally described as a marker of Hodgkin's and Reed-Sternberg cells in Hodgkin's lymphoma. Cloning and characterization of cDNAs encoding CD30 and its ligand (CD30L) …
CD30: from basic research to cancer therapy - PMC - PubMed …
Cluster determinant 30 (CD30) has been recognized since the 1980s by a monoclonal antibody (Ki-1) as an epitope of a membrane protein highly expressed on Reed–Sternberg and …
Diagnostic, prognostic and therapeutic role of CD30 in …
CD30 is a cell surface receptor expressed in classical Hodgkin lymphoma (HL), anaplastic large cell lymphoma (ALCL), and many other lymphomas to a variable degree. It has been identified …
CD30 expression in nonlymphomatous malignancies.
CD30 is the target of brentuximab vedotin (Adcetris), an antibody drug conjugate (ADC) that is approved for the treatment of patients with relapsed HL and systemic ALCL after failure of …
CD30 - an overview | ScienceDirect Topics
CD30 refers to a TNFR-related surface protein that is expressed by activated T and B cells. It was originally identified as a marker for the tumor cells of Hodgkin's lymphoma. CD30 has also …