CD11b, as an integrin molecule on the surface of leukocytes, plays an important role in cell migration, adhesion, and transmigration across blood vessels, because it can bind to …

2025年2月11日 · CD11b is a critical marker in immunology, primarily associated with myeloid cells. Its significance extends beyond basic research, influencing our understanding of immune …

Integrin αM (CD11b) is expressed in myeloid-lineage cells such as monocytes/macrophages, neutrophils, eosinophils, and basophils, and in lymphoid cells such as NK cells and peritoneal …

2022年11月15日 · Ablation or pharmacological inhibition of CD11b in mice significantly alleviated hypertension, aortic remodeling, superoxide generation, vascular dysfunction, and the …

2018年12月19日 · Here we report that, unexpectedly, integrin CD11b does not regulate myeloid cell recruitment to tumors but instead controls myeloid cell polarization and tumor growth. …

CD11b is a protein on immune cells like macrophages and microglia, aiding in cell adhesion, migration, and immune response. It’s used in immune and neuro research.

CD11b is an integrin family member which pairs with CD18 to form the CR3 heterodimer. CD11b is expressed on the surface of many leukocytes including monocytes, neutrophils, natural killer …

2015年4月22日 · Learn about CD11 and its role in adhesion-related association between cell and as a marker for macrophages and microglia, plus functional studies using CD11b antibodies.

The integrin CD11b/CD18 (also known as Mac-1), which is a heterodimer of the αM (CD11b) and β2 (CD18) subunits, is critical for leukocyte adhesion and migration and for immune functions. …

CD11b serves as a cell surface marker that aids in identifying and characterizing specific immune cell populations, particularly macrophages and microglia. Understanding the role of CD11b …