2024年12月24日 · CCL17 (C-C Motif Chemokine Ligand 17) is a Protein Coding gene. Diseases associated with CCL17 include Eosinophilic Pneumonia and Paragonimiasis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway.

Chemokine (C-C) ligand 17 (CCL17) was first identified as thymus- and activation-regulated chemokine when it was found to be constitutively expressed in the thymus and identified as a T-cell chemokine.

2023年4月19日 · Ccl17 knockout inhibited aging-induced vascular dysfunction. The aortas of young (4-month) and aged (21-month) WT and Ccl17 knockout (Ccl17-KO) male C57BL/6 mice were analyzed.

2023年3月28日 · CCL17 is elevated in many autoimmune/inflammatory diseases. CCL17, via its cognate receptor, CCR4, is traditionally viewed as a T-cell chemokine with its putative role mainly associated around Th2-driven pathology (e.g. atopic dermatitis and asthma) and Treg-driven pathology (e.g. Hodgkin's lymphoma and cancer metastasis). Recent studies have ...

More and more studies have shown that the interaction of C–C chemokine ligand 17 (CCL17) and C–C chemokine ligand 22 (CCL22) with the receptor C–C chemokine receptor type 4 (CCR4) promotes the immune escape of tumors and is closely related to the occurrence, development, and prognosis of hematological tumors.

2020年7月1日 · We explore, in this study and in various inflammation models, the cellular CCL17 expression and its GM-CSF dependence as well as the function of CCL17 in inflammation and pain.

CCL17 is an antimicrobial protein with bacteriocidal activity against E. coli and S. aureus. An association between TARC/CCL17 polymorphisms, susceptibility of Kawasaki disease, and intravenous immunoglobulin responses in Kawasaki disease patients.

CCL17, also known as Thymus and activation-regulated chemokine (TARC), is a type of chemokine that plays a role in recruiting lymphocytes and modulating immune function.

2020年7月1日 · We explore, in this study and in various inflammation models, the cellular CCL17 expression and its GM-CSF dependence as well as the function of CCL17 in inflammation and pain.

2024年12月30日 · CCL17 high-expression in THCA tumor microenvironment (TME) accelerates local infiltration of immune cells and enhances anticancer immunity, resulting in worse survival of patients and exerting potential prognostic value on tumor immunity in THCA.