
BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks …
Hoja informativa sobre los cambios en el gen BRCA y las pruebas …
Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.
MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
Those with harmful BRCA1 or BRCA2 changes who had the surgery, the study found, had a lower risk of dying from ovarian cancer and breast cancer than those who didn’t. Results from both …
Discovery – BRCA Connection to Breast and Ovarian Cancer
NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer. From this research, a screening test was also …
Definición de gen BRCA1 - Diccionario de cáncer del NCI
Gen que da origen a una proteína que repara el ADN dañado. Las mutaciones (cambios) en el gen BRCA1 aumentan mucho el riesgo de presentar cáncer de mama y cáncer de ovario.
Olaparib Approved for Breast Cancers with BRCA Gene Mutations
2018年1月29日 · The Food and Drug Administration has approved olaparib (Lynparza®) to treat metastatic breast cancers that have inherited mutations in the BRCA1 or BRCA2 genes as …
Cancer Risk for Women Carrying BRCA Mutations - NCI
2017年7月12日 · Women who know they have inherited a harmful BRCA1 or BRCA2 mutation can take steps to reduce their risk of breast and ovarian cancer. But any preventive …
Olaparib for Pancreatic Cancer with BRCA Mutations - NCI
2019年6月26日 · Olaparib (Lynparza) may benefit some people with advanced pancreatic cancer who have BRCA1 or BRCA2 mutations, according to the POLO trial results.
BRCA Gene Mutations: Cancer Risk and Genetic Testing
What do BRCA1 and BRCA2 genetic test results mean? How can a person who has inherited a harmful BRCA1 or BRCA2 gene variant reduce their risk of cancer? What are the benefits of …
PALB2 and Associated Cancer Risks (PDQ®) - NCI
2025年2月14日 · This gene interacts with both BRCA2 and BRCA1 to restore and maintain genomic stability via homologous recombination repair of DNA double-stranded breaks. …