2024年12月24日 · AMFR (Autocrine Motility Factor Receptor) is a Protein Coding gene. Diseases associated with AMFR include Spastic Paraplegia 89, Autosomal Recessive and Transitional …

2014年12月18日 · AMFR and INSIG1, an E3 ubiquitin ligase complex, then catalyzed the K27-linked polyubiquitination of STING. This modification served as an anchoring platform for …

2022年5月2日 · Here, we report that autocrine motility factor receptor (AMFR), an endoplasmic reticulum-resident E3 ubiquitin ligase, is upregulated in AMs of asthma and is critical for this …

2023年5月24日 · Quantitative image analysis revealed a ubiquitin-mediated increase in FAM134B oligomerization and cluster size. We found that the E3 ligase AMFR, within multimeric ER …

2025年2月8日 · Data show that autocrine motility factor receptor (AMFR) and NOTCH1 protein are the direct target genes of microRNA miR-139-5p in colorectal cancer (CRC). gp78 …

Autocrine motility factor receptor (AMFR) is an internalizing cell surface receptor that also exhibits ubiquitin E3 ligase activity in the endoplasmic reticulum. Stimulation of AMFR by its ligand …

Autocrine motility factor (AMF), a secreted cytokine, is known to alter the bone microenvironment by linking to its receptor AMFR (AMF Receptor), leading to tumor progression.

2025年1月4日 · Title: AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model. Expression of autocrine motility …

AMFR (Autocrine motility factor receptor) is an E3 ubiquitin-protein ligase that attaches ubiquitin tags to target proteins, marking them for degradation by the proteasome. It plays a key role in …

AMFR was initially described as a 78-kD internalizing cell surface receptor for autocrine motility factor (AMF; 172400), a protein secreted by tumor cells that stimulates tumor motility …